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Info on Mirtazapine:
It is an atypical antidepessant with nonadrenergic and specific serotonergic activity.
It blocks some adrenergic auto and heteroreceptors, increasing serotonin release, and selectively antagonizes serotonin receptors in the central and peripheral nervous system.
It also enhances serotonin neurotransmission and blocks the histaminergic and muscarinic receptors.
Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor but may increase serotonin and norepinephrine by other mechanisms of action.
Side Effects: Constipation, dry mouth, weight gain, increase appetite, somnolence, sedation, sleepiness, weakness, distrurbance in thinking, peripheral edema, increased blood pressure.
When Discontinuing Use:
Mirtazapine and other antidepressants may cause a discontinuation syndrome upon cessation. A GRADUAL and SLOW reduction in dose is recommended. Effects of sudden cessation of treatment with mirtazapine may include depression, anxiety, panic attacks, vertigo, restlessness, irritability, decreased appetite, insomnia, diarrhea, nausea, vomiting, flu-like symptoms such as allergies and pruritus, headaches and sometimes hypomania or mania. It can go so far as to cause suicidal thoughts, so please, be careful!!
AKA not good!!! PLEASE always been under the care of a great doctor and NEVER stop taking a drug suddenly without guidance from your doctor.
Some Drug Group Clusters:
Mirtazapine falls under – NaSSA (Noadrenergic & Specific Serotonergic Antidepressant)
SSRIs (Selective Serotonin Reuptake Inhibitors)
SNRIs (Serotonin-norepinephrine Reuptake Inhibitors)